Selenium as SelenoPrecise with selected antioxidants

Bio-Selenium+Zinc consist of tablets with the ingredients selenium, zinc, vitamin A, vitamin B6, vitamin C and vitamin E. The antioxidants in this unique complex that have been on the market for more than 25 years, supports, protects and complements each other, and their co-operative actions and high quality makes Bio-Selenium+Zinc the ideal antioxidant complex. Bio-Selenium+Zinc may also be used as an alternative to multi-vitamin preparations containing beta-carotene, which smokers may wish to avoid.
 

Contains SelenoPrecise^®

Bio-Selenium+Zinc contains 100 micrograms of selenium in the form of Pharma Nord's patented organic and easily absorbable SelenoPrecise selenium yeast. SelenoPrecise contains 67% selenium-methionine and 33% various other forms of selenium, which corresponds to the selenium forms we get from a diet rich in selenium. As much as 89% of the tablet's selenium is absorbed. Absorption and effect appears to be further increased when the selenium is combined with vitamin A, B6, C, E and zinc, wich are also organically bound.

Pharma Nord's patented selenium yeast is absorbed better than other organic and inorganic selenium forms.

Today, Pharma Nord is the only manufacturer in the world that has an approval to produce organic medical grade selenium yeast. This completely unique, patented medical raw material is used as a medicine in Denmark under the name SelenoPrecise, where the indication is prevention and treatment of selenium deficiency. All Pharma Nord's dietary supplements with selenium contain this original selenium yeast.

SelenoPrecise API (Active Pharmaceutical Ingredient)

Bio-Selenium + Zinc contains many different species of selenium, each of which has been shown to have different functions in our body. By supplying the body with a wide range of selenium species, it is possible to emulate the natural selenium variation found in a versatile diet. This means that the different selenium compounds can follow different biological pathways in the body and remain in the blood for varying periods of time. This is believed to have the greatest health benefit. Among the advantages of organically bound selenium species from selenium yeast are a higher absorption and bioavailability than from both inorganic selenium forms and synthetically produced selenomethionine.

The challenge: homogeneity

Production of homogeneous selenium yeast meaning it is similar from production batch to production batch, so that it qualifies for use as a medicine, is a difficult task. There are several reasons, not least that the tolerance requirements are so small. Thus, the permissible quantity deviation from the declared amount of selenium is very small, and at the same time, the content of the raw material of the different selenium forms must be similar from production to production. It makes sense, because of course you have to be able to count on being able to get the same effect from every single tablet.
Pharma Nord's selenium yeast contains more than 20 different selenium species, the content of organic selenium methionine selenomethionine is stable at 67%, and the proportion of inorganic selenium will not exceed 1% of the total amount of selenium.

Selenium compounds in SelenoPrecise

In analytical studies of SelenoPrecise selenium yeast, these selenium compounds have been identified:

Selenomethionine, selenomethionine selenium oxide (SeOMet), selenocysteine-se-methylselenocysteine, trimethylselenonium, selenomethylselenocysteine, selenomethylselenomethionine, gamma-glutamyl-se-methylselenocysteine, selenocysteine and polypeptides or low-molecular-celled polypeptides. In particular, the important selenocysteine-se-methylselenocysteine compounds, which are found in high amounts in garlic and which are considered to have a special protective effect, are optimized in SelenoPrecise compared to other selenium preparations.

Production of selenium yeast

Pharma Nord's selenium yeast is produced by fermentation. Live yeast cells (non-GMO) are "fed" ammonia as well as glucose, vitamins, minerals and inorganic selenium of pharmaceutical quality. The yeast cells will then incorporate and integrate the selenium into their cell walls and become part of the proteins in the yeast cells. In this way, the inorganic selenium has been changed to natural, organic selenium yeast.

The selenium yeast is then pasteurized, whereby the yeast cells die. The selenium-containing yeast cells are centrifuged, washed, frozen, pulverized, spray-dried, and compressed into tablets.

Summary

There are distinct advantages to taking API selenium yeast compared to taking other selenium forms.

• It is organic. The selenium content stays and acts longer in the body than inorganic selenium before it is excreted.
• It contains more than 20 different selenium compounds found in nature in a selenium-rich diet.
• It has a very small variation in the amount of its various selenium compounds.
• You get the same effect from tablet to tablet as with medical preparations.
• It has given the best results in scientific studies.

Antioxidants are substances that are able to neutralize free radicals which are chemically unstable molecules attacking everything around itself in a chain reaction. Both cell membranes and cell nuclei can be attacked whereby the cells are weakened and fatty acids are oxidized, that is, becoming rancid. We can not avoid free radicals because they are a natural consequence of our metabolism and are a consequence of, among others, stress. In some contexts, however, they also perform useful functions, but we continually need the protection of our cells, genetic material and fats against the unbridled mayhem of free radicals so that we can maintain the body's normal cellular functions as long as possible.

Antioxidants protect both against the free radicals from the body's own metabolism and from the free radicals generated in large quantities from the contaminated air, ozone and different types of radiation.

The European Food Safety Authority (EFSA) has evaluated the evidence behind the active ingredients and has acknowledged the following claims:

Selenium

• Contributes to a normal, well-functioning immune defense
• Contributes to normal functioning of the thyroid gland
• Supports normal sperm cell production
• Supports normal hair and nail growth
• Contributes to protecting the body’s cells
  against free radical damage

Vitamin A

• Contributes to normal cell division
• Necessary for normal immune function
• Supports normal skin and mucous membranes
• Helps to maintain normal vision

Vitamin B6

• Supports a normal and well-functioning immune defense
• Necessary for normal metabolism
• Necessary for a normal and well-functioning nervous system
• Necessary for producing normal red blood cells
• Part of the body’s normal energy metabolism
• Contributes to normal psyche
• Part of the body’s normal cysteine synthesis
• Necessary for the body’s hormonal balance
•  May help reduce fatigue and exhaustion

Vitamin C

• Part of a normal and well-functioning immune defense
• Contributes to normal functioning of the nervous system
• Contributes to normal collagen synthesis
• Part of the body’s normal energy metabolism
• Contributes to normal psyche
• Contributes to revitalizing used E-vitamin in the body
• Contributes to protecting the body’s cells against free radical damage
• Contributes to the absorption of non-heme iron (from fruit, vegetables, and grain products)
• May help reduce fatigue and exhaustion

Vitamin E

• Contributes to protecting the body’s cells against free radical damage

Zinc

• Part of normal DNA synthesis and cell division
• Contributes to a normal and well-functioning immune defense
• Supports normal fertility and reproduction
• Contributes to normal cognition and learning skills
• Part of a normal fatty acid metabolism
• Part of a normal acid-base balance
• Necessary for normal A-vitamin metabolism
• Contributes to maintaining hair, nails, skin, and bones
• Part of a normal protein synthesis in the body
• Contributes to normal levels of testosterone in the body
• Necessary for maintaining normal carbohydrate metabolism
• Important for normal vision
• Contributes to protecting the body’s cells against free radical damage