After each round of production, the machines are cleaned, effectively removing any trace of the former product and preparing the machines for the next production. The cleaning procedure is very time-consuming. In fact, the cleaning routines are that tedious it may take between 6 and 24 hours to prepare one single machine for the next round of production.
All cleaning procedures in the production area are validated, which means that their efficacy is proven so no products are exposed to contamination. The cleaning act is controlled and documented on check lists.